Residual ß-cell function and severe hypoglycemia, effect of hypoglycemia on thrombosis and inflammation, fasting glucose and nocturnal hypoglycemia, and role of insulin analogs and insulin pumps
Daniella Otway of the Diabetic Hypoglycemia Editorial Team
Diabetic Hypoglycemia January 2014, Volume 6, Issue 3: page 23-27
Residual β-cell function in children and adolescents with type 1 diabetes reduces risk of severe hypoglycemia
Sørensen et al recently showed that residual β-cell function (RBF) in children and adolescents 3–6 years after diagnosis of type 1 diabetes may limit hypoglycemia risk and benefit metabolic control. The study included 342 children aged 4.8–18.9 years with type 1 diabetes for 3–6 years from 16 pediatric diabetes centers within Denmark. Following an overnight fast, participants visited their usual outpatient clinic where they were provided with a standardized liquid breakfast meal.