News Article - severe hypoglycemia and brain development, artificial pancreas, and continuous glucose monitoring
Emily Chu, Nicole Meinel and Martin Gilmour of the Diabetic Hypoglycemia Editorial Team
Diabetic Hypoglycemia January 2012, Volume 4, Issue 3: page 21-22
Severe hypoglycemia and brain development
Previous research has revealed changes in hippocampal volumes in youth with type 1 diabetes; this may reflect a pathological reaction to hypoglycemia during brain development, such as gliosis, reactive neurogenesis, or disruption of the synaptic pruning that occurs during brain development. Other research has found evidence of qualitatively different relationships between hypo- and hyperglycemia and regional brain volumes in youth with type 1 diabetes.